"NOUNで、～。" means "Because of NOUN, ～～～".
"NOUNで、～。" means "Because of NOUN, ～～～".
This NOUN should be a bad event such as earthquake, disease, accident, etc...
e.g)
・地震(じしん)で、多(おお)くの人が亡(な)くなりました。
Because of the earthquake, many people died.
word)
多（おお）く [noun] many
人（ひと） [noun] person
亡（な）くなる [verb] to die
・病気で、学校を休みました。
Because of disease, I was absent from shool.
word)
病気（びょうき）[noun] disease
学校（がっこう）[noun] school
休（やす）む [verb] to be absent
～を休む be absent from ~.
Gracias!!
